From California to Pennsylvania, governors and mayors across the United States are tightening restrictions for COVID-19 amid an outbreak that is almost certainly made worse by Thanksgiving vacation trips and family reunions.

Authorities are closing businesses or limiting hours of operation, ordering or imploring people to stay home and maintain social distancing to help stop a wave of infections that threatens to overwhelm the country’s health system.

“I have to take the reins again,” New Jersey Gov. Phil Murphy said Monday, reducing the maximum number of people allowed in indoor gatherings from 25 to 10. “It does not give me joy.”

In California, Gov. Gavin Newsom has announced he will put “emergency brakes” on plans to resume economic activity as the state sees its largest growth in cases to date, which, if is left unattended, will have “catastrophic results”. The measure means shutting down many non-essential indoor businesses and requires the use of masks outside the home, with a few exceptions.

Meanwhile, Moderna Inc. has announced that its investigational coronavirus vaccine appears to be over 94% effective, based on preliminary results. A week ago, Pfizer revealed similar results with its own formula.

The news has raised hopes that at least two COVID-19 vaccines could obtain emergency clearance and be available in the United States before the end of 2020.

A record number of around 70,000 people were hospitalized with coronavirus in the United States on Sunday, 13,000 more than a week earlier, according to The COVID Tracking Project. Deaths in the United States are on average more than 1,100 a day, an increase of more than 50% from the beginning of October.

The virus has caused more than 246,000 deaths and more than 11 million confirmed infections in the United States.

Leaders across the country kept Thanksgiving in mind when they passed tighter restrictions, fearing the holidays could lead to an increase in infections.

“We really don’t want to see mom on Thanksgiving and bury her on Christmas,” said Dr. Mark Horne, president of the Mississippi State Medical Association, after the governor extended the mask order to more. counties Monday. “It’s going to happen. They’ll say “hello” on Thanksgiving, “it was nice to see you,” and then they’ll have to visit him or have a video call in the intensive care unit or plan a little funeral before Christmas. “

In New Mexico, Gov. Michelle Lujan Grisham’s housebound order went into effect Monday. Only businesses deemed essential, such as grocery stores and pharmacies, will be opened.

Washington Gov. Democrat Jay Inslee has ordered gyms, bowling alleys, cinemas, museums and zoos closed. Stores must limit their capacity to 25%.

People who do not share a home will be banned from meeting in Washington state, unless they have been quarantined. There is no mechanism to monitor compliance with the measure. Inslee said she expects people to follow through.

Chicago Mayor Lori Lightfoot has called on residents of the nation’s third largest city to limit their meetings to a maximum of 10 people starting Monday. In his instructions, which are not mandatory, he urged residents to stay at home except for essential activities, such as going to work or buying food.

Philadelphia has banned indoor food service and indoor gatherings of any size, public or private, between people who do not live under the same roof, effective Friday.

In Michigan, Democratic Housekeeper Gretchen Whitmer warned that, if necessary, she had the power to issue a second lockdown order to contain the spread of the coronavirus, and that President Donald Trump’s science adviser Scott Atlas was ” incredibly reckless. ”By calling on the population to“ stand up ”against the latest state restrictions.

Over the weekend, Whitmer announced the suspension of face-to-face classes at high schools and colleges, canceled indoor food service and ordered entertainment centers to close for three weeks. The size of the meetings will also be limited.

Fourteen men were indicted last month over an alleged conspiracy to kidnap the governor because they were upset by the restrictions she put in place to fight COVID-19.

In a subsequent tweet, Atlas said he would “never” encourage or incite violence.

Even North Dakota Republican Gov. Doug Burgum, who has opposed ordering the use of masks for several months, implemented such restrictions over the weekend amid a severe outbreak in the ‘State.

However, several other Republican governors were taking or opposed progressive action and continued to favor “personal responsibility” over government orders. Oklahoma President Republican Kevin Stitt announced that all bars and restaurants must leave a distance of 1.8 meters (6 feet) between tables and suspend in-person service at 11 p.m.

In South Dakota, a state hit hard by the pandemic, Governor Kristi Noem has opposed ordering the use of masks and other restrictions.

Texas Governor Gregg Abbott has stressed in recent days that new treatments and vaccines should be available soon.

Vice President Mike Pence continued his optimism Monday during a conference call with governors, noting that the federal government is ready to help states where hospitals are near full capacity and stressing that vaccines do not take long to run. come.

“The United States has never been so prepared to fight this virus,” he said.

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